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A molecular trigger for intercontinental epidemics of group A Streptococcus

10 Aug 2015

Abstract excerpt

The identification of the molecular events responsible for strain emergence, enhanced virulence, and epidemicity has been a long-pursued goal in infectious diseases research. A recent analysis of 3,615 genomes of serotype M1 group A Streptococcus strains (the so-called "flesh-eating" bacterium) identified a recombination event that coincides with the global M1 pandemic beginning in the early 1980s. Here, we have...

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PMID: 26258415
DOI: 10.1172/jci82478

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