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Article

Acquisition of the Sda1-encoding bacteriophage does not enhance virulence of the serotype M1 Streptococcus pyogenes strain SF370.

Infection and immunity - 1 Jun 2013

Venturini Carola, Ong Cheryl-Lynn Y, Gillen Christine M, Ben-Zakour Nouri L, Maamary Peter G, Nizet Victor, Beatson Scott A, Walker Mark J

Abstract excerpt

The resurgence of invasive disease caused by Streptococcus pyogenes (group A Streptococcus [GAS]) in the past 30 years has paralleled the emergence and global dissemination of the highly virulent M1T1 clone. The GAS M1T1 clone has diverged from the ancestral M1 serotype by horizontal acquisition of two unique bacteriophages, encoding the potent DNase Sda1/SdaD2 and the superantigen SpeA, respectively. The...

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PMID: 23529618
DOI: 10.1128/IAI.00192-13
PMCID: PMC3676029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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