Article
Dissection of the molecular basis for hypervirulence of an in vivo-selected phenotype of the widely disseminated M1T1 strain of group A Streptococcus bacteria.
The Journal of infectious diseases - 15 Mar 2010
Kansal Rita G, Datta Vivekanand, Aziz Ramy K, Abdeltawab Nourtan F, Rowe Sarah, Kotb Malak
Abstract excerpt
Group A streptococci (GAS) may engage different sets of virulence strategies, depending on the site of infection and host context. We previously isolated 2 phenotypic variants of a globally disseminated M1T1 GAS clone: a virulent wild-type (WT) strain, characterized by a SpeB(+)/SpeA(-)/Sda1(low)...
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