Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mapping the protein interaction network for TFIIB-related factor Brf1 in the RNA polymerase III preinitiation complex.

Molecular and cellular biology - 1 Feb 2014

Khoo Seok-Kooi, Wu Chih-Chien, Lin Yu-Chun, Lee Jin-Cheng, Chen Hung-Ta

Abstract excerpt

TFIIB-related factor Brf1 is essential for RNA polymerase (Pol) III recruitment and open-promoter formation in transcription initiation. We site specifically incorporated a nonnatural amino acid cross-linker into Brf1 to map its protein interaction targets in the preinitiation complex (PIC). Our cross-linking analysis in the N-terminal domain of Brf1 indicated a pattern of multiple protein interactions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Western
Share to Protein Interaction Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Interaction Maps

Share to RNA Polymerase III

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Share to TATA-Box Binding Protein

Share to Transcription Factor TFIIB

Source

Open in PubMed Open full text

Identifiers

PMID: 24277937
DOI: 10.1128/MCB.00910-13
PMCID: PMC3911497

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mapping the protein interaction network for TFIIB-related factor Brf1 in the RNA polymerase III preinitiation complex.PMID 24277937Read ↗

A common site on TBP for transcription by RNA polymerases II and III.Semantic proximity Read ↗

The positions of TFIIF and TFIIE in the RNA polymerase II transcription preinitiation complex.Semantic proximity Read ↗

The role of transcription initiation factor IIIB subunits in promoter opening probed by photochemical cross-linking.Semantic proximity Read ↗

Binding of TFIIB to RNA polymerase II: Mapping the binding site for the TFIIB zinc ribbon domain within the preinitiation complex.Semantic proximity Read ↗

Structure of the BRK domain of the SWI/SNF chromatin remodeling complex subunit BRG1 reveals a potential role in protein–protein interactionsSemantic proximity Read ↗

Evolutionary Conservation of Structural and Functional Coupling between the BRM AT-Hook and Bromodomain.Semantic proximity Read ↗

BRCT Domain Interactions in the Heterodimeric DNA Repair Protein XRCC1−DNA Ligase IIISemantic proximity Read ↗

Structure of an XRCC1 BRCT domain: a new protein-protein interaction module.Semantic proximity Read ↗

Function of Conserved Topological Regions within the Saccharomyces cerevisiae Basal Transcription Factor TFIIH.Semantic proximity Read ↗

Distinct Mechanisms of Recognition of Phosphorylated RNAPII C-Terminal Domain by BRCT Repeats of the BRCA1–BARD1 Complex: Insights from Structural and Functional AnalysesSemantic proximity Read ↗

Probing the conformation of the ISWI ATPase domain with genetically encoded photoreactive crosslinkers and mass spectrometry.Semantic proximity Read ↗

The Saccharomyces cerevisiae RNA polymerase III recruitment factor subunits Brf1 and Bdp1 impose a strict sequence preference for the downstream half of the TATA box.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.