Article
[Micronuclei and genetic polymorphisms: from exposure to susceptibility].
Annales de biologie clinique - 1 Jan 2000
Iarmarcovai G, Botta A, Orsière T
Abstract excerpt
The concept of genetic susceptibility and interactions between genetic and environmental factors of risk is a new trend in molecular epidemiology studies of cancers. Micronuclei are biomarkers of chromosome damage due to genetic instability or exposure to environmental mutagens or carcinogens. The micronucleus assay in combination with fluorescent in situ hybridization discriminates between micronuclei containing...
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