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Article

Biomarkers of genetic damage for cancer epidemiology.

Toxicology - 27 Dec 2002

Fenech Michael

Abstract excerpt

Cancer is a disease of altered gene expression involving a complex array of epigenetic events, gene mutation, chromosome rearrangements and altered chromosome number. The coincidence of genotoxic events with the induction of cancer has fueled great interest in molecular/cytogenetic epidemiological studies aimed at linking polymorphisms in genes for DNA repair and carcinogen metabolism and biomarkers of...

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PMID: 12505344
DOI: 10.1016/s0300-483x(02)00480-8

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