Article
Human population studies with cytogenetic biomarkers: review of the literature and future prospectives.
Environmental and molecular mutagenesis - 1 Jan 2000
Bonassi Stefano, Ugolini Donatella, Kirsch-Volders Micheline, Strömberg Ulf, Vermeulen Roel, Tucker James D
Abstract excerpt
Cytogenetic biomarkers are by far the most frequently used endpoints in human population studies. Their sensitivity for measuring exposure to genotoxic agents and their role as early predictors of cancer risk have contributed to this success. In this article, we present an overview of the last 25 years of population studies with cytogenetic biomarkers, describing the evolution of this research and addressing the...
Topics
- Chromosome Aberrations
- Cytogenetic Analysis
- Genetic Markers
- Genetic Predisposition to Disease
- Humans
- Micronucleus Tests
- Molecular Epidemiology
- Statistics as Topic
