Clinical application of micronucleus test: a case-control study on the prediction of breast cancer risk/susceptibility.

doi:10.1371/journal.pone.0112354

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Article

Clinical application of micronucleus test: a case-control study on the prediction of breast cancer risk/susceptibility.

PloS one - 1 Jan 2014

Bolognesi Claudia, Bruzzi Paolo, Gismondi Viviana, Volpi Samantha, Viassolo Valeria, Pedemonte Simona, Varesco Liliana

Abstract excerpt

The micronucleus test is a well-established DNA damage assay in human monitoring. The test was proposed as a promising marker of cancer risk/susceptibility mainly on the basis of studies on breast cancer. Our recent meta-analysis showed that the association between micronuclei frequency, either at baseline or after irradiation, and breast cancer risk or susceptibility, has been evaluated in few studies of small...

Topics

Adult
Aged
Breast Neoplasms
Case-Control Studies
Female
Genetic Predisposition to Disease
Humans
Micronucleus Tests
Middle Aged

Source

Open in PubMed Open full text

Identifiers

PMID: 25415331
DOI: 10.1371/journal.pone.0112354
PMCID: PMC4240584

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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