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Article

Study design and statistical analysis of data in human population studies with the micronucleus assay.

Mutagenesis - 1 Jan 2011

Ceppi Marcello, Gallo Fabio, Bonassi Stefano

Abstract excerpt

The most common study design performed in population studies based on the micronucleus (MN) assay, is the cross-sectional study, which is largely performed to evaluate the DNA damaging effects of exposure to genotoxic agents in the workplace, in the environment, as well as from diet or lifestyle factors. Sample size is still a critical issue in the design of MN studies since most recent studies considering...

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PMID: 21164209
DOI: 10.1093/mutage/geq060

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