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Article

Genetic polymorphisms and micronucleus formation: a review of the literature.

Mutation research - 1 Jan 2000

Iarmarcovai G, Bonassi S, Botta A, Baan R A, Orsière T

Abstract excerpt

The formation of micronuclei (MN) is extensively used in molecular epidemiology as a biomarker of chromosomal damage, genome instability, and eventually of cancer risk. The occurrence of MN represents an integrated response to chromosome-instability phenotypes and altered cellular viabilities caused by genetic defects and/or exogenous exposures to genotoxic agents. The present article reviews human population...

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Source

Identifiers

PMID: 18037339
DOI: 10.1016/j.mrrev.2007.10.001

Genes

ALDH2
BRCA1
BRCA2
GSTM1
GSTT1
MTHFR
XRCC1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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