Article
Comparative genetics and innate immune functions of collagenous lectins in animals.
Veterinary immunology and immunopathology - 18 Oct 2005
Lillie Brandon N, Brooks Andrew S, Keirstead Natalie D, Hayes M Anthony
Abstract excerpt
Collagenous lectins such as mannan-binding lectins (MBLs), ficolins (FCNs), surfactant proteins A and D (SP-A, SP-D), conglutinin (CG), and related ruminant lectins are multimeric proteins with carbohydrate-binding domains aligned in a manner that facilitates binding to microbial surface polysaccharides. MBLs and FCNs are structurally related to C1q, but activate the lectin complement pathway via interaction with...
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