Article
Extensive variation in the mouse intelectin gene family: recent duplications, deletions and inactivating variants result in diversity in laboratory strains
2021-03-31
Abstract excerpt
Intelectins are a family of multimeric secreted proteins that bind microbe-specific glycans. Both genetic and functional studies have suggested that intelectins have an important role in innate immunity and are involved in the etiology of various human diseases, including inflammatory bowel disease. Experiments investigating the role of intelectins in human disease using mouse models are limited by the fact that t...
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Identifiers and source
- Literature Corpus work
- 637ec076-3a4c-5d87-a033-e7a573792633
- DOI
- 10.1101/2021.03.31.437930