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Article

Hypoxia-inducible factor-1alpha (HIF-1alpha) gene polymorphisms, circulating insulin-like growth factor binding protein (IGFBP)-3 levels and prostate cancer.

The Prostate - 1 Sept 2007

Li Haojie, Bubley Glenn J, Balk Stephen P, Gaziano J Michael, Pollak Michael, Stampfer Meir J, Ma Jing

Abstract excerpt

BACKGROUND: The Hypoxia-inducible factor-1 (HIF-1) plays an important role in regulating angiogenesis in response to hypoxia. Two non-synonymous polymorphisms (P582S C-->T and A588T G-->A) in the coding region of the subunit 1alpha (HIF-1alpha) gene have been associated with enhanced stability of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neovascularization, Pathologic

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Source

Identifiers

PMID: 17624927
DOI: 10.1002/pros.20589

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17624927-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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