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Article

Non-Latin European descent could be a requirement for association of NTDs and MTHFR variant 677C > T: a meta-analysis.

American journal of medical genetics. Part A - 1 Aug 2007

Amorim Márcia R, Lima Marcelo A C, Castilla Eduardo E, Orioli Iêda M

Abstract excerpt

There are several studies that have found a positive association between neural tube defects (NTDs) and the common mutation 677C > T of 5,10-methylenetetrahydrofolate reductase (MTHFR), and others that have not found such an association. We updated the meta-analyses of the published data about NT...

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Source

Identifiers

PMID: 17618486
DOI: 10.1002/ajmg.a.31812

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17618486-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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