Article
Bile acids promote the expression of hepatitis C virus in replicon-harboring cells.
Journal of virology - 1 Sept 2007
Chang Kyeong-Ok, George David W
Abstract excerpt
Hepatitis C virus (HCV) is a cause of chronic liver disease, with more than 170 million persistently infected individuals worldwide. Although the combination therapy of alpha interferon (IFN-alpha) and ribavirin is effective for chronic HCV infection, around half of all patients infected with HCV genotype 1 fail to show sustained virologic responses and remain chronically infected. Previously, we demonstrated...
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