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Article

Inhibition of subgenomic hepatitis C virus RNA in Huh‐7 cells: ribavirin induces mutagenesis in HCV RNA

20 Oct 2004

Abstract excerpt

Hepatitis C virus (HCV) infection is a major problem throughout the world. Combination therapy of interferon (IFN) and ribavirin is the best treatment for eradication at present, but the mechanism is not completely understood. We used the HCV replicon system to investigate this mechanism. The effects of six drugs (UDCA, glycyrrhizin, TJ-9, bezafibrate, ribavirin, and alpha-IFN 2b) on HCV subgenomic RNA (genotype...

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Identifiers

PMID: 15500548
DOI: 10.1111/j.1365-2893.2004.00531.x

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