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Article

Hepatitis C virus replicons escape RNA interference induced by a short interfering RNA directed against the NS5b coding region.

Journal of virology - 1 Jun 2005

Wilson Joyce A, Richardson Christopher D

Abstract excerpt

RNA interference represents an exciting new technology that could have therapeutic applications for the treatment of viral infections. Hepatitis C virus (HCV) is a major cause of chronic liver disease and affects over 270 million individuals worldwide. The HCV genome is a single-stranded RNA that functions as both an mRNA and a replication template, making it an attractive target for therapeutic approaches using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15890944
DOI: 10.1128/JVI.79.11.7050-7058.2005
PMCID: PMC1112103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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