Comparison of protein tyrosine phosphorylation and morphological changes induced by IL-2 and IL-3.

doi:10.1093/intimm/3.11.1137

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Article

Comparison of protein tyrosine phosphorylation and morphological changes induced by IL-2 and IL-3.

International immunology - 1 Nov 1991

Sabe H, Kuno J, Koromilas A, Saito Y, Kinashi T, Ueda M, Takamatsu T, Hamaguchi M, Kawakami T, Honjo T

Abstract excerpt

We constructed cell lines which can proliferate in response to IL-2 or IL-3 by introducing a wild-type and mutant forms of cDNAs encoding the human IL-2R p75 chain into an IL-3 dependent hematopoietic cell line which expresses the p55 chain of the IL-2R. We compared early events that were induced...

Topics

Base Sequence
Cell Line
DNA
Humans
Interleukin-2
Interleukin-3
Molecular Sequence Data
Mutation
Phosphorylation
Proteins
Receptors, Interleukin-2
Tyrosine

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