Activation of leukemic large granular lymphocytes by interleukin-2 via the p75 interleukin-2 receptor.

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Article

Activation of leukemic large granular lymphocytes by interleukin-2 via the p75 interleukin-2 receptor.

Leukemia - 1 Dec 1990

Yoon H J, Sugamura K, Loughran T P

Abstract excerpt

We studied the role of interleukin-2 (IL-2) receptor subunits in the activation of leukemic CD3+ large granular lymphocytes (LGL). Peripheral blood mononuclear cells from four patients with CD3+ LGL leukemia were activated with 500 mu/ml of recombinant IL-2. Induction of both proliferative and cy...

Topics

Antibodies, Monoclonal
Antigens, CD
Antigens, Differentiation, T-Lymphocyte
CD3 Complex
Cell Division
Humans
Interleukin-2
Leukemia
Lymphocyte Activation
Phenotype
Receptors, Antigen, T-Cell
Receptors, Interleukin-2
Recombinant Proteins
T-Lymphocytes

Source

Open in PubMed

Identifiers

PMID: 2147047

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2147047-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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