Article
The role of IL-2 interaction with p75 and p55 receptor molecules in the stimulation of cell proliferation.
International immunology - 1 May 1993
Perkins G R, Flemming C L, Kabat D, Collins M K
Abstract excerpt
This report addresses the role of individual IL-2 binding proteins of the IL-2 receptor in the stimulation of cell proliferation by IL-2. Murine IL-3-dependent cell lines were established which expressed the human p75 IL-2-binding protein, in the absence or presence of the human p55 IL-2-binding protein. Whereas p75 expression was sufficient to confer response to an intermediate (half-maximal stimulation at 100...
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