Induction of tyrosine phosphorylation by the erythropoietin receptor correlates with mitogenesis.

doi:10.1128/mcb.11.10.4895-4902.1991

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Article

Induction of tyrosine phosphorylation by the erythropoietin receptor correlates with mitogenesis.

Molecular and cellular biology - 1 Oct 1991

Miura O, D'Andrea A, Kabat D, Ihle J N

Abstract excerpt

A role for tyrosine phosphorylation in the signal-transducing mechanisms of several hematopoietic growth factors has been hypothesized. To extend these observations, we have examined the effects of erythropoietin (Epo) on tyrosine phosphorylation in an Epo-responsive cell that was obtained by transfecting the murine erythropoietin receptor (EpoR) into an interleukin-3 (IL-3)-dependent cell line. By...

Topics

Amino Acid Sequence
Base Sequence
Cell Division
Cell Line
Enzyme Induction
Erythropoietin
Gene Expression Regulation
Immunoblotting
Interleukin-3
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phosphorylation

Receptors, Cell Surface

Receptors, Erythropoietin

Receptors, Interleukin-2

Sequence Homology, Nucleic Acid

Transfection

Tyrosine

Source

Open in PubMed Open full text

Identifiers

PMID: 1656216
DOI: 10.1128/mcb.11.10.4895-4902.1991
PMCID: PMC361458

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1656216-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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