Article
In vitro phosphorylation of the erythropoietin receptor and an associated protein, pp130.
Molecular and cellular biology - 1 Feb 1992
Yoshimura A, Lodish H F
Abstract excerpt
The cytoplasmic domain of the cloned erythropoietin (EPO) receptor (EPOR) contains no protein kinase motif, yet addition of EPO to EPO-responsive cells causes an increase in protein-tyrosine phosphorylation. Here we show that addition of EPO or interleukin-3 (IL-3) to an IL-3-dependent cell line...
Topics
- Amino Acid Sequence
- Animals
- Biotin
- Cell Division
- Cell Line
- Cloning, Molecular
- Erythropoietin
- Interleukin-3
- Mice
- Molecular Sequence Data
- Mutation
- Phosphoproteins
- Phosphorylation
- Precipitin Tests
- Protein Kinases
- Receptors, Cell Surface
- Receptors, Erythropoietin
- Transfection