Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Different mechanisms of activation of proliferating CD3+ cells in patients with lymphoproliferative disease of granular lymphocytes.

Leukemia - 1 Nov 1991

Zambello R, Cassatella M A, Trentin L, Bulian P, Siviero F, Feruglio C, Agostini C, Vespignani M, Chisesi T, Pizzolo G

Abstract excerpt

To investigate the role of p55 and p75 chains of interleukin-2 receptor (IL-2R) on the activation of granular lymphocytes (GL) in patients with lymphoproliferative disease of granular lymphocytes (LDGL), the cells obtained from 11 LDGL patients (belonging to the CD3+ group) were studied for (a) the surface expression and (b) mRNA transcripts of the p55 and p75 IL-2R after activation with anti-CD3 monoclonal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Antibodies, Monoclonal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Blotting, Northern

Share to Interleukin-2

Share to Lymphocyte Activation

Share to Phenotype

Share to Receptors, Antigen, T-Cell

Share to RNA, Messenger

Source

Identifiers

PMID: 1835747

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Different mechanisms of activation of proliferating CD3+ cells in patients with lymphoproliferative disease of granular lymphocytes.PMID 1835747Read ↗

Cell membrane expression and functional role of the p75 subunit of interleukin-2 receptor in lymphoproliferative disease of granular lymphocytes.Semantic proximity Read ↗

Activation of leukemic large granular lymphocytes by interleukin-2 via the p75 interleukin-2 receptor.Semantic proximity Read ↗

Proliferative responses to PHA, anti-CD3 and antigens in patients with lymphoproliferative disease of granular lymphocytes. Mannoproteins of Candida albicans induce proliferation and cytotoxicity.Semantic proximity Read ↗

Clonally expanded CD3+, CD4-, CD8- cells bearing the alpha/beta or the gamma/delta T-cell receptor in patients with the lymphoproliferative disease of granular lymphocytes.Semantic proximity Read ↗

Anti-CD3 monoclonal antibody-mediated cytotoxicity occurs through an interleukin-2-independent pathway in CD3+ large granular lymphocytes.Semantic proximity Read ↗

Molecular analysis of T cell receptor and CD3 genes in CD3- large granular lymphocytes (LGLs): evidence for the existence of CD3- LGLs committed to the T cell lineage.Semantic proximity Read ↗

[Biological and clinical characteristics of granular lymphocyte proliferation. Review of the literature and personal experience].Semantic proximity Read ↗

T-lymphocyte subpopulations do not express identical combinations of interleukin-2 receptor chains in the early phase of their activation and proliferation.Semantic proximity Read ↗

Comparison of protein tyrosine phosphorylation and morphological changes induced by IL-2 and IL-3.Semantic proximity Read ↗

Natural killer cells activated by interleukin 2 treatment in vivo respond to interleukin 2 primarily through the p75 receptor and maintain the p55 (TAC) negative phenotype.Semantic proximity Read ↗

Upregulation of CXCR1 by proliferating cells in patients with lymphoproliferative disease of granular lymphocytes.Semantic proximity Read ↗

Different activation states of human lymphocytes after antibody-mediated stimulation via CD3 and the alpha/beta T-cell receptor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.