Different mechanisms of activation of proliferating CD3+ cells in patients with lymphoproliferative disease of granular lymphocytes.

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Article

Different mechanisms of activation of proliferating CD3+ cells in patients with lymphoproliferative disease of granular lymphocytes.

Leukemia - 1 Nov 1991

Zambello R, Cassatella M A, Trentin L, Bulian P, Siviero F, Feruglio C, Agostini C, Vespignani M, Chisesi T, Pizzolo G

Abstract excerpt

To investigate the role of p55 and p75 chains of interleukin-2 receptor (IL-2R) on the activation of granular lymphocytes (GL) in patients with lymphoproliferative disease of granular lymphocytes (LDGL), the cells obtained from 11 LDGL patients (belonging to the CD3+ group) were studied for (a) t...

Topics

Adult
Aged
Antibodies, Monoclonal
Antigens, Differentiation, T-Lymphocyte
Blotting, Northern
CD3 Complex
Cell Separation
Female
Humans
Interleukin-2
Lymphocyte Activation
Lymphoproliferative Disorders
Male
Middle Aged
Phenotype

Source

Open in PubMed

Identifiers

PMID: 1835747

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1835747-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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RNA, Messenger

Receptors, Antigen, T-Cell

Receptors, Interleukin-2