Article
Biochemical and immunological phenotype alterations in human monoblastoid cell line U-937 induced by physiological (interferon-alpha, retinoic acid) and nonphysiological (phorbol ester) inducers.
Neoplasma - 1 Jan 1990
Chorváth B, Sedlák J, Duraj J, Klobusická M, Plesková I, Augustinová M, Suliková M
Abstract excerpt
Human monoblastoid cell line U-937 was induced by recombinant or leukocyte human interferon-alpha, retinoic acid, by their combination, or by 12-0-tetradecanoyl-phorbol-13-acetate (TPA), to express some differentiation-associated markers and characteristics. Induced biochemical alterations were studied with the aid of two-dimensional electrophoretic analysis (isoelectrofocusing/SDS-PAGE) of 125I-lactoperoxidase...
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