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Article

A specific box switches the cell fate determining activity of XOTX2 and XOTX5b in the Xenopus retina.

Neural development - 27 Jun 2007

Onorati Marco, Cremisi Federico, Liu Yang, He Rong-Qiao, Barsacchi Giuseppina, Vignali Robert

Abstract excerpt

BACKGROUND: Otx genes, orthologues of the Drosophila orthodenticle gene (otd), play crucial roles in vertebrate brain development. In the Xenopus eye, Xotx2 and Xotx5b promote bipolar and photoreceptor cell fates, respectively. The molecular basis of their differential action is not completely understood, though the carboxyl termini of the two proteins seem to be crucial. To define the molecular domains that make...

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Identifiers

PMID: 17597530
DOI: 10.1186/1749-8104-2-12
PMCID: PMC1929070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A specific box switches the cell fate determining activity of XOTX2 and XOTX5b in the Xenopus retina.PMID 17597530Read ↗

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