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Article

Role of Pax genes in eye evolution: a cnidarian PaxB gene uniting Pax2 and Pax6 functions.

Developmental cell - 1 Nov 2003

Kozmik Zbynek, Daube Michael, Frei Erich, Norman Barbara, Kos Lidia, Dishaw Larry J, Noll Markus, Piatigorsky Joram

Abstract excerpt

PaxB from Tripedalia cystophora, a cubomedusan jellyfish possessing complex eyes (ocelli), was characterized. PaxB, the only Pax gene found in this cnidarian, is expressed in the larva, retina, lens, and statocyst. PaxB contains a Pax2/5/8-type paired domain and octapeptide, but a Pax6 prd-type homeodomain. Pax2/5/8-like properties of PaxB include a DNA binding specificity of the paired domain, activation and...

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PMID: 14602077
DOI: 10.1016/s1534-5807(03)00325-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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