Article
The mammalian Crx genes are highly divergent representatives of the Otx5 gene family, a gnathostome orthology class of orthodenticle-related homeogenes involved in the differentiation of retinal photoreceptors and circadian entrainment.
Molecular biology and evolution - 1 Apr 2003
Plouhinec Jean-Louis, Sauka-Spengler Tatjana, Germot Agnès, Le Mentec Chantal, Cabana Thérèse, Harrison Gavan, Pieau Claude, Sire Jean-Yves, Véron Géraldine, Mazan Sylvie
Abstract excerpt
The mammalian Crx genes are highly divergent orthodenticle (otd)-related homeogenes that play important roles in the differentiation of retinal photoreceptors and the circadian entrainment. However, their evolutionary origin and orthological relationships with other otd-related genes remain unclear. An orthology relationship of these genes with the highly conserved Otx5 genes identified in fish and amphibians,...
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