Article
Association of a single nucleotide polymorphism in the WISP1 gene with spinal osteoarthritis in postmenopausal Japanese women.
Journal of bone and mineral metabolism - 1 Jan 2007
Urano Tomohiko, Narusawa Ken'ichiro, Shiraki Masataka, Usui Takahiko, Sasaki Noriko, Hosoi Takayuki, Ouchi Yasuyoshi, Nakamura Toshitaka, Inoue Satoshi
Abstract excerpt
The Wnt-beta-catenin signaling pathway that regulates bone density is also involved in cartilage development and homeostasis in vivo. Here, we assumed that genetic variation in Wnt-beta-catenin signaling genes can affect the pathogenesis of cartilage related diseases, such as osteoarthritis. Wnt-...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
