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Article

WISP3‐dependent regulation of type II collagen and aggrecan production in chondrocytes

1 Feb 2004

Abstract excerpt

OBJECTIVE: WISP3 (Wnt-1-inducible secreted protein 3) is a member of the CCN (connective tissue growth factor, cysteine-rich 61, nephroblastoma overexpressed) family of connective tissue growth factors. WISP3 mutations have been linked to progressive pseudorheumatoid dysplasia (PPRD). The present study was conducted to investigate whether WISP3 is responsible for the expression of cartilage-specific molecules....

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PMID: 14872491
DOI: 10.1002/art.20005

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