Article
Q89R Polymorphism in the LDL Receptor-Related Protein 5 Gene Is Associated With Spinal Osteoarthritis in Postmenopausal Japanese Women
1 Jan 2007
Abstract excerpt
In Brief Study Design. An association study investigating the genetic etiology for spinal osteoarthritis. Objective. To determine the association of single-nucleotide polymorphism (SNP) causing an amino-acid change (Q89R) in the low-density lipoprotein receptor-related protein 5 (LRP5) coding region with spinal osteoarthritis. Summary of Background Data. Wnt/β-catenin signaling pathway regulates bone density...
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