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Article

A microsatellite polymorphism in intron 2 of human Toll-like receptor 2 gene: functional implications and racial differences.

FEMS immunology and medical microbiology - 8 Mar 2004

Yim Jae-Joon, Ding Li, Schäffer Alejandro A, Park Gye Young, Shim Young-Soo, Holland Steven M

Abstract excerpt

The human Toll-like receptor 2 (TLR2) mediates responses of both innate and adaptive immunity to Gram-positive bacteria, including mycobacteria. We sought functional polymorphisms in the 5'-untranslated region (UTR) of TLR2. We found a highly polymorphic (GT)n dinucleotide repeat 100 bp upstream of the TLR2 translational start site in intron 2. The numbers of GT repeats varied from 12 to 28. There were...

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Source

Identifiers

PMID: 14987735
DOI: 10.1016/S0928-8244(03)00342-0

Genes

TLR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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