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Article

No association of CSF biomarkers with APOEepsilon4, plaque and tangle burden in definite Alzheimer's disease.

Brain : a journal of neurology - 1 Sept 2007

Engelborghs Sebastiaan, Sleegers Kristel, Cras Patrick, Brouwers Nathalie, Serneels Sally, De Leenheir Evelyn, Martin Jean-Jacques, Vanmechelen Eugeen, Van Broeckhoven Christine, De Deyn Peter Paul

Abstract excerpt

The CSF biomarkers beta-amyloid peptide (Abeta(1-42)), total tau protein (T-tau) and tau phosphorylated at threonine 181 (P-tau(181P)) were determined in autopsy-confirmed Alzheimer's disease patients in order to study possible associations with the epsilon4 allele of APOE and density and spread of plaques (SP) and tangles (NFT). CSF levels of Abeta(1-42), T-tau and P-tau(181P) were determined in 50 Alzheimer's...

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Source

Identifiers

PMID: 17586559
DOI: 10.1093/brain/awm136

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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