Article
Association of CSF apolipoprotein E, Abeta42 and cognition in Alzheimer's disease.
Neurobiology of aging - 1 Jan 2000
Riemenschneider M, Schmolke M, Lautenschlager N, Vanderstichele H, Vanmechelen E, Guder W G, Kurz A
Abstract excerpt
A significant association between CSF Abeta42 and cognition in patients with Alzheimer's disease (AD) homozygous for the epsilon3 allele of the apolipoprotein E (apoE) has been described. In this study we extended our observations on apoE, as another plaque component, and investigated the association between CSF apoE concentrations and cognitive performance after stratification for the apoE genotype in 62...
Topics
- Aged
- Alzheimer Disease
- Amyloid beta-Peptides
- Apolipoproteins E
- Cognition
- Female
- Genotype
- Humans
- Male
- Neuropsychological Tests
- Peptide Fragments
