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Article

CSF beta-amyloid, cognition, and APOE genotype in Alzheimer's disease.

Neurology - 1 Feb 1999

Samuels S C, Silverman J M, Marin D B, Peskind E R, Younki S G, Greenberg D A, Schnur E, Santoro J, Davis K L

Abstract excerpt

OBJECTIVES: We examined the relationship between CSF amyloid beta peptide (A beta) concentration and AD severity in 31 probable AD patients and explored whether APOE genotype modifies this relationship. BACKGROUND: A beta deposition in AD brains has been correlated with disease severity and with APOE-epsilon4 allele frequency. Few studies have examined the effects of APOE genotype on the relationship between CSF...

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Source

Identifiers

PMID: 10025785
DOI: 10.1212/wnl.52.3.547

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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