Article
Common variation in the BRCA1 gene and prostate cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2007
Douglas Julie A, Levin Albert M, Zuhlke Kimberly A, Ray Anna M, Johnson Gregory R, Lange Ethan M, Wood David P, Cooney Kathleen A
Abstract excerpt
Rare inactivating mutations in the BRCA1 gene seem to play a limited role in prostate cancer. To our knowledge, however, no study has comprehensively assessed the role of other BRCA1 sequence variations (e.g., missense mutations) in prostate cancer. In a study of 817 men with and without prostate cancer from 323 familial and early-onset prostate cancer families, we used family-based association tests and...
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