Article
A replication study examining novel common single nucleotide polymorphisms identified through a prostate cancer genome-wide association study in a Japanese population.
American journal of epidemiology - 15 Dec 2011
Batra Jyotsna, Lose Felicity, Chambers Suzanne, Gardiner Robert A, Aitken Joanne, Yaxley John, Clements Judith A, Spurdle Amanda B
Abstract excerpt
Five novel prostate cancer risk loci were identified in a recent genome-wide association study (GWAS) of Japanese persons (Takata et al., Nat Genet. 2010;42(9):751-754). Those authors proposed that apart from population-specific linkage disequilibrium patterns, limitations of GWAS single nucleotide polymorphism (SNP) prioritization and/or study design could explain the lack of identification of these loci in GWAS...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.