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Article

A rare 8q24 single nucleotide polymorphism (SNP) predisposes North American men to prostate cancer and possibly more aggressive disease.

BJU international - 1 Jan 2015

Grin Boris, Loeb Stacy, Roehl Kim, Cooper Phillip R, Catalona William J, Helfand Brian T

Abstract excerpt

OBJECTIVE: To assess the frequency of a novel prostate cancer-associated single nucleotide polymorphism (SNP), rs188140481, in a North American population and to evaluate the clinical significance of this variant including annotated prostatectomy pathology. PATIENTS/SUBJECTS AND METHODS: We examined the frequency of the minor allele at rs188140481 in 4299 North American men including 1979 men with prostate cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24952954
DOI: 10.1111/bju.12847
PMCID: PMC4268414

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