Article
Akt2 Gene common allelic variants in insulin resistance and the metabolic syndrome.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 May 2008
Tassi Vittorio, Coco Angelo, Padovano Libera, De Bonis Concetta, De Cosmo Salvatore, Trischitta Vincenzo
Abstract excerpt
BACKGROUND AND AIM: Several lines of evidence indicate that glucose homeostasis may be under the control of Akt2 and it can therefore be seen as a candidate gene for human insulin resistance (IR) and related phenotypes. The aim of our study was the identification of Akt2 common allelic variants that might modulate susceptibility to IR and related metabolic abnormalities. METHODS AND RESULTS: The Akt2 gene (exons,...
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