Article
Single nucleotide polymorphisms within functional regions of genes implicated in insulin action and association with the insulin resistant phenotype.
Molecular and cellular biochemistry - 1 Mar 2011
Malodobra Malgorzata, Pilecka Agnieszka, Gworys Bohdan, Adamiec Rajmund
Abstract excerpt
Type 2 diabetes and insulin resistance (IR) are characterized by severe anomalies in genes expression rate including genes involved in insulin signal transduction. Post-transcriptional regulation of gene expression is crucial for many physiological processes and is mediated mainly by untranslated region (UTR). Present study concentrated on the search for correlation between single nucleotides polymorphisms in...
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