Article
Diffusion-ordered nuclear magnetic resonance spectroscopy for analysis of DNA secondary structural elements.
Analytical biochemistry - 1 Aug 2007
Ambrus Attila, Yang Danzhou
Abstract excerpt
Structure determination of secondary DNA structural elements, such as G-quadruplexes, gains an increasing importance as fundamental physiological roles are being associated with the formation of such structures in vivo. A truncated native DNA sequence generally requires further optimization to obtain a candidate with desired nuclear magnetic resonance (NMR) properties for structural analysis in solution. The...
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