Article
Contribution of Burkholderia cenocepacia flagella to infectivity and inflammation.
Infection and immunity - 1 Sept 2004
Urban Teresa A, Griffith Adam, Torok Anastasia M, Smolkin Mark E, Burns Jane L, Goldberg Joanna B
Abstract excerpt
Burkholderia cenocepacia is an opportunistic pathogen that can cause severe lung infections in cystic fibrosis patients. To understand the contribution of B. cenocepacia flagella to infection, a strain mutated in the major flagellin subunit, fliCII, was constructed in B. cenocepacia K56-2 and tested in a murine agar bead model of lung infection. C57/BL6 mice infected with approximately 10(8) wild-type K56-2...
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