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Flagellar motility and the mucus environment influence aggregation mediated antibiotic tolerance of <i>Pseudomonas aeruginosa</i> in chronic lung infection

2024-10-25

Abstract excerpt

<h4>ABSTRACT</h4> Pseudomonas aeruginosa frequently causes chronic lung infection in individuals with muco-obstructive airway diseases (MADs). Chronic P. aeruginosa infections are difficult to treat, primarily owing to antibiotic treatment failure, which is often observed in the absence of antimicrobial resistance. In MADs, P. aeruginosa forms biofilm-like aggregates within the luminal mucus. While the contribu...

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Literature Corpus work
459ca718-600b-55a7-80b9-3793048f1970
DOI
10.1101/2024.10.25.620240
Open publication

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Flagellar motility and the mucus environment influence aggregation mediated antibiotic tolerance of <i>Pseudomonas aeruginosa</i> in chronic lung infectionDOI 10.1101/2024.10.25.620240
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