Article
Mutations in TrpI binding site II that differentially affect activation of the trpBA promoter of Pseudomonas aeruginosa.
The EMBO journal - 1 Dec 1991
Gao J, Gussin G N
Abstract excerpt
In vitro, Pseudomonas aeruginosa TrpI protein activates transcription initiation at the trpBA promoter (trpPB) and represses initiation at its own promoter (trpPI), which diverges from, and overlaps, trpPB. Indoleglycerol phosphate (InGP) reduces the TrpI concentration required for binding to its strong binding site (site I), as measured by repression of trpPI; it also facilitates activation of trpPB, presumably...
Topics
- Bacterial Proteins
- Base Sequence
- Binding Sites
- DNA Fingerprinting
- DNA, Bacterial
- DNA-Binding Proteins
- Gene Expression Regulation, Bacterial
- Gene Expression Regulation, Enzymologic
- Genes, Bacterial
- Glycerophosphates