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Article

Up-promoter mutations in the trpBA operon of Pseudomonas aeruginosa.

Journal of bacteriology - 1 Jun 1991

Han C Y, Crawford I P, Harwood C S

Abstract excerpt

In Pseudomonas aeruginosa, the operon encoding tryptophan synthase (trpBA) is positively regulated by the TrpI protein and an intermediate in tryptophan biosynthesis, indoleglycerol phosphate (InGP). A gene fusion in which the trpBA promoter directs expression of the Pseudomonas putida xylE gene was constructed. By using a P. putida F1 todE mutant carrying this fusion on a plasmid, three cis-acting mutations that...

Topics

Bacterial Proteins
Bacteriophages
Base Sequence
DNA-Binding Proteins
Genes, Bacterial
Genes, Viral
Molecular Sequence Data
Mutagenesis, Site-Directed
Mutation
Operon
Plasmids
Promoter Regions, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pseudomonas aeruginosa

Trans-Activators

Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 1904857
DOI: 10.1128/jb.173.12.3756-3762.1991
PMCID: PMC208005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1904857-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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