Transcription of the trp operon in Lactococcus lactis is controlled by antitermination in the leader region.

doi:10.1099/00221287-144-8-2103

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Article

Transcription of the trp operon in Lactococcus lactis is controlled by antitermination in the leader region.

Microbiology (Reading, England) - 1 Aug 1998

Frenkiel HéléeGne, Bardowski Jacek, Ehrlich S Dusko, Chopin Alain

Abstract excerpt

The regulatory functions of the leader region preceding the Lactococcus lactis trp operon have been studied by mutagenesis analysis. This leader presents striking similarity to 'T-box' leaders found upstream of many Gram-positive aminoacyl-tRNA synthetase genes and some amino acid biosynthesis operons, which are controlled by antitermination through interaction of the leader transcript with cognate uncharged...

Topics

Base Sequence
Blotting, Northern
Codon, Terminator
Lactococcus lactis
Molecular Sequence Data
Mutation
Operon
RNA
Regulatory Sequences, Nucleic Acid
Sequence Analysis, RNA
Transcription, Genetic
Tryptophan
Ultraviolet Rays

Source

Open in PubMed

Identifiers

PMID: 9720031
DOI: 10.1099/00221287-144-8-2103

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