Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RNA structure inhibits the TRAP (trp RNA-binding attenuation protein)-RNA interaction.

The Journal of biological chemistry - 16 Oct 1998

Xirasagar S, Elliott M B, Bartolini W, Gollnick P, Gottlieb P A

Abstract excerpt

TRAP (trp RNA-binding attenuation protein) regulates expression of the tryptophan biosynthetic genes in response to tryptophan in Bacillus subtilis by binding to two sites containing a series of 9 or 11 (G/U)AG triplet repeats that are generally separated by two or three spacer nucleotides. Previous mutagenesis experiments have identified three TRAP residues, Lys-37, Lys-56, and Arg-58 that are essential for RNA...

Topics

Bacillus
Bacterial Proteins
Binding Sites
Circular Dichroism
Conserved Sequence
Guanosine
Mutation
Nucleic Acid Conformation
Nucleic Acid Denaturation
Protein Binding
RNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA-Binding Proteins

Selection, Genetic

Spectrophotometry, Ultraviolet

Transcription Factors

Source

Identifiers

PMID: 9765233
DOI: 10.1074/jbc.273.42.27146

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RNA structure inhibits the TRAP (trp RNA-binding attenuation protein)-RNA interaction.PMID 9765233Read ↗

trp RNA-binding attenuation protein-5' stem-loop RNA interaction is required for proper transcription attenuation control of the Bacillus subtilis trpEDCFBA operon.Semantic proximity Read ↗

The anti-trp RNA-binding attenuation protein (Anti-TRAP), AT, recognizes the tryptophan-activated RNA binding domain of the TRAP regulatory protein.Semantic proximity Read ↗

Creating hetero-11-mers composed of wild-type and mutant subunits to study RNA binding to TRAP.Semantic proximity Read ↗

Effects of mutations in the L-tryptophan binding pocket of the Trp RNA-binding attenuation protein of Bacillus subtilis.Semantic proximity Read ↗

trp RNA-binding attenuation protein (TRAP)-trp leader RNA interactions mediate translational as well as transcriptional regulation of the Bacillus subtilis trp operon.Semantic proximity Read ↗

The structure of trp RNA-binding attenuation protein.Semantic proximity Read ↗

RNA and protein complexes of trp RNA-binding attenuation protein characterized by mass spectrometry.Semantic proximity Read ↗

The Bacillus subtilis TRAP protein can induce transcription termination in the leader region of the tryptophan biosynthetic (trp) operon independent of the trp attenuator RNA.Semantic proximity Read ↗

A temperature-sensitive trpS mutation interferes with trp RNA-binding attenuation protein (TRAP) regulation of trp gene expression in Bacillus subtilis.Semantic proximity Read ↗

Dynamic allostery in the ring protein TRAP.Semantic proximity Read ↗

Transcription of the trp operon in Lactococcus lactis is controlled by antitermination in the leader region.Semantic proximity Read ↗

Identification of a Residue (Glu60) in TRAP Required for Inducing Efficient Transcription Termination at the trp Attenuator Independent of Binding Tryptophan and RNA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.