trp RNA-binding attenuation protein (TRAP)-trp leader RNA interactions mediate translational as well as transcriptional regulation of the Bacillus subtilis trp operon.

Abstract excerpt

Expression of the Bacillus subtilis trpEDCFBA operon has been shown to be regulated by transcription attenuation in response to the availability of L-tryptophan. Regulation is mediated by the tryptophan-activated trp RNA-binding attenuation protein, TRAP, the product of mtrB. Formation of mutually exclusive RNA anti-terminator and terminator structures within trp leader RNA determines whether transcription will...

Topics

• Bacillus subtilis
• Bacterial Proteins
• Base Sequence
• Gene Expression Regulation, Bacterial
• Molecular Sequence Data
• Mutation
• Nucleic Acid Conformation
• Operon
• Protein Biosynthesis
• RNA, Bacterial