Article
Evaluation of AC(n) and C(-106)T polymorphisms of the aldose reductase gene in Brazilian patients with DM1 and susceptibility to diabetic retinopathy.
Molecular vision - 23 May 2007
Richeti Flávio, Noronha Renata Maria, Waetge Ricardo Temudo Lessa, de Vasconcellos José Paulo Cabral, de Souza Osías Francisco, Kneipp Bianca, Assis Nilma, Rocha Mylene Neves, Calliari Luís Eduardo Procópio, Longui Carlos Alberto, Monte Osmar, de Melo Monica Barbosa
Abstract excerpt
PURPOSE: Diabetic retinopathy (DR) is one of the most important microvascular complications in both type 1 and type 2 diabetes. In Brazil, its proliferative form is the second cause of irreversible blindness among adults of working age. Despite the strong association of DR with disease duration and degree of chronic hyperglycemia, genetic predisposition has been recognized as a possible trigger in the development...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.