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Article

Aldose reductase gene polymorphisms and diabetic retinopathy susceptibility.

Diabetes care - 1 Aug 2010

Abhary Sotoodeh, Burdon Kathryn P, Laurie Kate J, Thorpe Stacey, Landers John, Goold Lucy, Lake Stewart, Petrovsky Nikolai, Craig Jamie E

Abstract excerpt

OBJECTIVE: Aldose reductase (ALR) is involved in diabetic microvascular damage via the polyol pathway. A recent meta-analysis found genetic variation in the ALR gene (AKR1B1) to be significantly associated with diabetic retinopathy (DR). We investigated the genetic association of AKR1B1 with DR. RESEARCH DESIGN AND METHODS: The study enrolled 909 individuals with diabetes. Participants were genotyped for an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cardiac Ischemia and Reperfusion

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Source

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Identifiers

PMID: 20424224
DOI: 10.2337/dc09-1893
PMCID: PMC2909072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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