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Article

Association between Aldose Reductase Gene C(-106)T Polymorphism and Diabetic Retinopathy: A Systematic Review and Meta-Analysis.

Ophthalmic research - 1 Jan 2020

Lin Shan, Peng Yuanzheng, Cao Mengtao, Chen Ruiting, Hu Jiying, Pu Zuhui, Cai Zhiming, Mou Lisha

Abstract excerpt

Controversial results regarding the associations between aldose reductase (AR) genetic polymorphisms and diabetic retinopathy (DR) have been reported for many years. The present meta-analysis was performed to clarify the effects of the AR gene C(-106)T polymorphism on DR risk. The PubMed, Web of Sciences, Cochrane library, EMBASE, Chinese National Knowledge Infrastructure, and Wan Fang databases were extensively...

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PMID: 31962334
DOI: 10.1159/000503972

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